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Likely active: new deal Sep 2025 Verified 5 Nov 2026

645 Ventures

New York, NY early-stage venture firm, also in San Francisco, investing across enterprise, deep tech, AI infrastructure, fintech, consumer, cybersecurity and health tech.

Type
VC firm
Location
New York, New York, United States
Stages
Series A, Growth
Backs
B2B software, Fintech, Medtech and digital health, Deep tech
Sectors
AI, Fintech, Healthtech and life sciences, Cybersecurity, B2B, Deep tech, Consumer, Devtools
Fund size / AUM
$194.5M 645 Ventures IV (Form D offering, 2022); $593.7M gross private fund assets (Form ADV; private funds: 5, of which venture capital: 5)
Latest fund or filing
13 Jun 2023

Contacts on file

For 645 Ventures, the paid file holds: 2 named decision-makers with roles; how to pitch (the route the firm publishes); LinkedIn page.

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Sources

Last checked 5 Nov 2026. Is something wrong? Tell us.

Appears in 78 lists

Growth-stage developer tools investors in the US (24)Developer tools investors in New York (31)Cybersecurity investors in New York (33)B2B investors in New York (34)Growth-stage developer tools investors (39)Deep tech investors in New York (42)Growth-stage deep tech investors in the US (43)Series A investors in New York (49)Series A developer tools investors in the US (50)Medtech investors in New York (53)Growth-stage B2B investors in the US (54)Growth-stage cybersecurity investors in the US (55)Growth-stage investors in New York (57)Consumer investors in New York (59)Growth-stage consumer investors in the US (60)Series A cybersecurity investors in the US (64)Series A developer tools investors (67)Growth-stage medtech investors in the US (69)Series A deep tech investors in the US (73)Series A medtech investors in the US (76)Series A B2B investors in the US (79)Series A consumer investors in the US (80)Growth-stage cybersecurity investors (92)Growth-stage fintech investors in the US (97)Fintech investors in New York (98)Healthtech investors in New York (100)Growth-stage medtech investors (107)Series A cybersecurity investors (118)Growth-stage B2B investors (119)Growth-stage healthtech investors in the US (121)Growth-stage consumer investors (124)Series A medtech investors (125)SaaS investors in New York (138)Series A fintech investors in the US (145)Series A consumer investors (154)Series A B2B investors (157)AI investors in New York (159)Growth-stage AI investors in the US (162)Growth-stage SaaS investors in the US (162)Series A healthtech investors in the US (164)Developer tools venture capital firms in the US (177)Growth-stage deep tech investors (191)Cybersecurity venture capital firms in the US (214)Growth-stage fintech investors (214)Developer tools investors (216)Series A SaaS investors in the US (256)B2B venture capital firms in the US (257)Series A AI investors in the US (280)Growth-stage investors in the US (288)Series A deep tech investors (293)Series A fintech investors (294)Growth-stage AI investors (295)Cybersecurity investors (316)Growth-stage healthtech investors (316)Deep tech venture capital firms in the US (322)Growth-stage SaaS investors (344)Consumer venture capital firms in the US (348)Medtech venture capital firms in the US (350)Series A investors in the US (372)Series A healthtech investors (401)B2B investors (438)Venture capital firms in New York (440)Medtech investors (457)Series A SaaS investors (475)Series A AI investors (500)Consumer investors (512)Fintech venture capital firms in the US (525)Growth-stage investors (705)Healthtech venture capital firms in the US (709)Deep tech investors (763)Fintech investors (846)Series A investors (864)SaaS venture capital firms in the US (1,049)AI venture capital firms in the US (1,112)Healthtech investors (1,207)SaaS investors (1,529)AI investors (1,576)Venture capital firms in the US (2,975)