48 biotech investors in Silicon Valley
We list 48 biotech investors in Silicon Valley as of November 2026: each has an SEC filing on file, and the list was last checked on 6 Nov 2026. The cities with the most head offices on this list are Palo Alto (16), Menlo Park (12) and San Mateo (6).
Top 5 biotech investors in Silicon Valley, ranked by recent fund activity
Among firms with a published profile and a dated fund or deal in the last 24 months. The rule: Activity score out of 100: recency of the latest fund filing or dated deal (35: full marks within 3 months, then stepping down at 6, 12 and 24 months), share of the observed portfolio in this sector (25; half of that when the sector is stated only), stated focus on the US (15: full marks when the firm names the US as where it invests, half when it says global), size of the fund on file on a log scale (15) and completeness of the public record (10). Regional focus is our research, not an SEC figure. It is a measure of activity and fit, not of quality or returns. The same rule orders the whole list; it is repeated in the method box.
Longitude Venture Partners
Type: VC firm · HQ: Menlo Park, CA · Stages: Growth · Focus: Biotech, Healthtech, Medtech · Latest activity: New deal, Jun 2026 · Fund size on file: $600M (SEC Form D, 2022)
Dated new deal in Jun 2026; $600M fund on file (SEC Form D, 2022); 80% of its observed portfolio is biotech and life sciences; names the US as where it invests; 8 named decision-makers on file.
TCGX
Type: VC firm · HQ: Palo Alto, CA · Focus: Biotech, Healthtech · Latest activity: New fund, Oct 2026 · Fund size on file: $600M (SEC Form D, 2026)
Latest fund filing dated Oct 2026; $600M fund on file (SEC Form D, 2026); 96% of its observed portfolio is biotech and life sciences; 8 named decision-makers on file.
Mitsui & Co. Global Investment, Inc.
Type: Corporate VC · HQ: Menlo Park, CA · Focus: Biotech, Healthtech, AI, Industrial Tech · Latest activity: Portfolio news, Jun 2026 · Private fund assets: $142M (SEC Form ADV)
Portfolio news dated Jun 2026; $142M on file (SEC Form ADV); 38% of its observed portfolio is biotech and life sciences; names the US as where it invests; 3 named decision-makers on file.
Felicis
Type: VC firm · HQ: Menlo Park, CA · Stages: Seed, Series A · Focus: Biotech, AI, Developer Tools, Healthtech · Latest activity: New deal, Oct 2026 · Fund size on file: $900M (SEC Form D, 2025)
Dated new deal in Oct 2026; $900M fund on file (SEC Form D, 2025); states biotech and life sciences as a focus; 8 named decision-makers on file.
True Ventures
Type: VC firm · HQ: Palo Alto, CA · Stages: Pre-seed, Seed · Focus: Biotech, AI, Fintech, Deep Tech · Latest activity: New fund, Sep 2026 · Fund size on file: $800M (SEC Form D, 2022)
Latest fund filing dated Sep 2026; $800M fund on file (SEC Form D, 2022); 7% of its observed portfolio is biotech and life sciences; names the US as where it invests; 8 named decision-makers on file.
First 24 of 48 biotech investors in Silicon Valley
| Investor | Type | HQ | Stagesour research | Focusour research | Latest fund or deal | Fund sizeas filed or stated | Checked | Contacts |
|---|---|---|---|---|---|---|---|---|
| Longitude Venture Partners | VC firm | Menlo Park, CA | Growth | Biotech, Healthtech, Medtech | New deal, Jun 2026 | $600M (SEC Form D, 2022) | 5 Nov 2026 | 8 names · Unlock |
| TCGX | VC firm | Palo Alto, CA | Biotech, Healthtech | New fund, Oct 2026 | $600M (SEC Form D, 2026) | 4 Nov 2026 | 8 names, firm email · Unlock | |
| Mitsui & Co. Global Investment, Inc. | Corporate VC | Menlo Park, CA | Biotech, Healthtech, AI, Industrial Tech | Portfolio news, Jun 2026 | $142M (SEC Form ADV) | 5 Nov 2026 | 3 names · Unlock | |
| Felicis | VC firm | Menlo Park, CA | Seed, Series A | Biotech, AI, Developer Tools, Healthtech | New deal, Oct 2026 | $900M (SEC Form D, 2025) | 5 Nov 2026 | 8 names · Unlock |
| True Ventures | VC firm | Palo Alto, CA | Pre-seed, Seed | Biotech, AI, Fintech, Deep Tech | New fund, Sep 2026 | $800M (SEC Form D, 2022) | 4 Nov 2026 | 8 names · Unlock |
| Future Ventures | VC firm | Los Altos, CA | Seed | Biotech, Healthtech, AI, Energy | New fund, Oct 2026 | $200M (SEC Form D, 2021) | 4 Nov 2026 | 4 names · Unlock |
| Sofinnova | VC firm | Menlo Park, CA | Biotech, Healthtech | New fund, Jun 2026 | $550M (SEC Form D, 2024) | 4 Nov 2026 | 8 names, firm email · Unlock | |
| DCVC | VC firm | Palo Alto, CA | Biotech, Energy, Healthtech, AI | New fund, Oct 2026 | $800M (SEC Form D, 2025) | 4 Nov 2026 | 4 names · Unlock | |
| Draper Associates | VC firm | San Mateo, CA | Pre-seed, Seed, Series A | Biotech, AI, Fintech, Healthtech | New fund, Oct 2026 | $301M (SEC Form D, 2025) | 4 Nov 2026 | 8 names · Unlock |
| 3i Partners | VC firm | Los Altos, CA | Pre-seed, Seed | Biotech, Mobility, Healthtech, Deep Tech | New fund, May 2026 | $24M (SEC Form D, 2025) | 5 Nov 2026 | 8 names · Unlock |
| Nanodimension | VC firm | Woodside, CA | Any stage | Biotech, Healthtech, Deep Tech | $594M (SEC Form ADV) | 5 Nov 2026 | 5 names, firm email · Unlock | |
| Andreessen Horowitz (a16z) | VC firm | Menlo Park, CA | Seed, Series A, Series B, Growth | Biotech, AI, Defense Tech, Healthtech | New fund, Aug 2026 | 4 Nov 2026 | 2 names · Unlock | |
| Phoenix Venture Partners | VC firm | San Mateo, CA | Seed | Biotech, AI, Healthtech, Energy | Portfolio news, Jul 2026 | $109M (SEC Form D, 2021) | 5 Nov 2026 | 8 names · Unlock |
| Pear Ventures | VC firm | Menlo Park, CA | Pre-seed, Seed | Biotech, AI, Fintech, Healthtech | New fund, Oct 2026 | $410M (SEC Form D, 2022) | 4 Nov 2026 | 8 names · Unlock |
| Frazier Life Sciences | VC firm | Palo Alto, CA | Pre-seed, Seed, Series A, Series B, Growth | Biotech, Healthtech | New fund, Mar 2025 | $7.0B (SEC Form ADV) | 5 Nov 2026 | 6 names · Unlock |
| ShangBay Capital | VC firm | Palo Alto, CA | Seed | Biotech, Healthtech, Medtech | New deal, Jan 2025 | $48M (SEC Form D, 2021) | 5 Nov 2026 | 7 names · Unlock |
| Calculus VC | VC firm | Foster City, CA | Series A, Series B | Biotech, AI, Deep Tech, Healthtech | New deal, Aug 2026 | $1M (SEC Form D, 2025) | 4 Nov 2026 | 1 name, firm email · Unlock |
| DC Global Ventures | VC firm | Menlo Park, CA | Seed, Growth | Biotech, Healthtech, Industrial Tech, Medtech | $2.7B (SEC Form ADV) | 5 Nov 2026 | 8 names · Unlock | |
| ACVC Partners | VC firm | Palo Alto, CA | Seed | Biotech, AI, Deep Tech, Mobility | New fund, Dec 2024 | $50M (SEC Form D, 2024) | 5 Nov 2026 | 8 names · Unlock |
| Innovation Endeavors | VC firm | Palo Alto, CA | Seed | Biotech, AI, Robotics, Healthtech | New deal, Feb 2026 | $600M (SEC Form D, 2023) | 5 Nov 2026 | 8 names · Unlock |
| Dalena Capital | VC firm | Palo Alto, CA | Seed | Biotech, Healthtech | New fund, May 2026 | $5M (SEC Form D, 2025) | 4 Nov 2026 | 1 name · Unlock |
| NTI | VC firm | Mountain View, CA | Seed, Series A | Biotech, Healthtech, Mobility, Medtech | $56M (SEC Form ADV) | 5 Nov 2026 | LinkedIn page · Unlock | |
| Fusion Fund | VC firm | Palo Alto, CA | Pre-seed, Seed, Series A | Biotech, AI, Healthtech, Industrial Tech | New fund, Jun 2024 | $526M (SEC Form ADV) | 5 Nov 2026 | 8 names · Unlock |
| Better Capital | VC firm | Santa Clara, CA | Pre-seed, Seed | Biotech, AI, Healthtech, Climate Tech | Portfolio news, Mar 2026 | $60M (SEC Form D, 2022) | 5 Nov 2026 | 6 names · Unlock |
You are seeing 24 of 48. The full list adds 24 more investors and 250 named decision-makers.
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How these 48 break down
By city
| City | On this list | Share |
|---|---|---|
| Palo Alto | 16 | 33% |
| Menlo Park | 12 | 25% |
| San Mateo | 6 | 12% |
| Santa Clara | 4 | 8% |
| Los Altos | 3 | 6% |
| Foster City | 2 | 4% |
| Mountain View | 2 | 4% |
By stage
| Stage | On this list | Share |
|---|---|---|
| Pre-Seed | 14 | 29% |
| Seed | 31 | 65% |
| Series A | 12 | 25% |
| Series B | 7 | 15% |
| Growth | 7 | 15% |
Stage is our research. A firm can back more than one stage.
By type
| Type | On this list | Share |
|---|---|---|
| VC firm | 46 | 96% |
| Corporate VC | 1 | 2% |
| Government or university fund | 1 | 2% |
Method and limits
- Source
- All 48 rows carry an SEC filing (Form D or Form ADV). 47 of the 48 have a website we checked; the other 1 rests on the filing or register entry alone. Filing date and fund size are SEC data where a filing exists. Stage, sector and check size are our research.
- Inclusion rule
- Organizations that back startups. Individuals, buyout funds and firms we found to be inactive are left out. Sector: the firm states biotech and life sciences as a focus on its own site, or we observed it in the firm's portfolio. Place: head office in Silicon Valley, matched on city and state.
- Order
- Firms with a published profile come first. Activity score out of 100: recency of the latest fund filing or dated deal (35: full marks within 3 months, then stepping down at 6, 12 and 24 months), share of the observed portfolio in this sector (25; half of that when the sector is stated only), stated focus on the US (15: full marks when the firm names the US as where it invests, half when it says global), size of the fund on file on a log scale (15) and completeness of the public record (10). Regional focus is our research, not an SEC figure. It is a measure of activity and fit, not of quality or returns.
- Last refreshed
- November 2026. Rows on this list were checked between 4 Nov 2026 and 6 Nov 2026.
- Fill rates
- Of 48 rows: stage 37, sector 48, fund size 44, website 47. In the paid file: named decision-makers on 45 rows, firm email on 10, LinkedIn page on 21, check size on 0.
- Corrections
- Email hello@theinvestordatabase.com or use the update form. We act within 5 working days.
Questions
How many biotech investors in Silicon Valley are there?
We list 48 as of November 2026. 23 of the 48 have a fund filing or a dated deal in the last 12 months. The cities with the most are Palo Alto (16), Menlo Park (12) and San Mateo (6).
Which biotech investors in Silicon Valley raised a new fund in the last 12 months?
16 of the 48 have a fund filing dated in the last 12 months. The most recent on this list are Future Ventures (Oct 2026), Draper Associates (Oct 2026) and Pear Ventures (Oct 2026).
What is the typical fund size of biotech investors in Silicon Valley?
The median fund size on file for this list is $100M, across the 32 firms with a size on an SEC Form D. The fund on file is each firm's main fund, which is not always its newest. The other 16 do not disclose a size there.
How do I contact biotech investors in Silicon Valley?
The paid file holds 250 named decision-makers across 45 of these 48 and a firm email for 10. We publish the address a firm lists itself, never a personal email. Each free row links to a profile with the firm's website.
Where does the data on biotech investors in Silicon Valley come from?
All 48 rows have an SEC filing on file (Form D or Form ADV). Filing date and fund size come from the filing. Stage, sector and check size are our research. Rows on this list were last checked on 6 Nov 2026 at the latest. The whole file is re-verified twice a year.
Broader lists
Biotech venture capital firms in the US (297)Venture capital firms in Silicon Valley (341)Venture capital firms in California (1,038)
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