---
title: "225 Pre-seed Healthtech Investors in the US (Nov 2026)"
last_updated: "2026-11-06"
rows: "225"
free_rows: "25"
source: "SEC filings"
canonical: "https://theinvestordatabase.com/lists/pre-seed-healthtech-investors-us/"
---

# 225 pre-seed healthtech investors in the US

We list 225 pre-seed healthtech investors in the US as of November 2026: each has an SEC filing on file, and the list was last checked on 6 Nov 2026. The cities with the most head offices on this list are New York (30), San Francisco (19) and Palo Alto (17).

- 225 investors
- 140 with a fund filing or dated deal in the last 12 months
- $50M median fund size on file (SEC Form D, 178 firms)
- 1,162 named decision-makers on file

## First 25 of 225 pre-seed healthtech investors in the US

| Investor | Type | HQ | Stages (our research) | Focus (our research) | Latest fund or deal | Fund size | Checked | Profile |
|---|---|---|---|---|---|---|---|---|
| SOSV | VC firm | United States | Pre-seed | Healthtech, Deep Tech, Climate Tech, Biotech | Portfolio news, Nov 2026 | $131M (SEC Form D, 2022) | 2026-11-04 | https://theinvestordatabase.com/investors/sosv/ |
| Redbud VC | VC firm | Columbia, MO | Pre-seed | Healthtech, Agritech, AI, Climate Tech | New fund, Sep 2026 | $25M (SEC Form D, 2025) | 2026-11-04 | https://theinvestordatabase.com/investors/redbud-vc/ |
| New Stack | VC firm | Chicago, IL | Pre-seed, Seed | Healthtech, AI, Fintech, Industrial Tech | New fund, Sep 2026 | $125M (SEC Form D, 2024) | 2026-11-04 | https://theinvestordatabase.com/investors/new-stack/ |
| 1616 Ventures | VC firm | Nashville, TN | Pre-seed | Healthtech, SaaS, Medtech | New fund, Aug 2026 | $150M (SEC Form D, 2026) | 2026-11-04 | https://theinvestordatabase.com/investors/1616-ventures/ |
| Avid Ventures | VC firm | New York, NY | Pre-seed | Healthtech, AI, Fintech, SaaS | Portfolio news, Oct 2026 | $75M (SEC Form D, 2021) | 2026-11-05 | https://theinvestordatabase.com/investors/avid-ventures/ |
| Khosla Ventures | VC firm | Menlo Park, CA | Pre-seed, Seed, Series A, Growth | Healthtech, AI, Consumer, B2B | New fund, Aug 2026 | $1.9B (SEC Form D, 2025) | 2026-11-04 | https://theinvestordatabase.com/investors/khosla-ventures/ |
| Slauson & Co | VC firm | Los Angeles, CA | Pre-seed, Seed | Healthtech, AI, Fintech, Logistics | New deal, Sep 2026 | $100M (SEC Form D, 2023) | 2026-11-05 | https://theinvestordatabase.com/investors/slauson-co/ |
| M25 | VC firm | Chicago, IL | Pre-seed, Seed | Healthtech, AI, Generalist, Fintech | New deal, Sep 2026 | $50M (SEC Form D, 2022) | 2026-11-05 | https://theinvestordatabase.com/investors/m25/ |
| LightX Capital | VC firm | Chicago, IL | Pre-seed | Healthtech, AI, Robotics, SaaS | New fund, Nov 2026 |  | 2026-11-04 | https://theinvestordatabase.com/investors/lightx-capital/ |
| Alliance Venture Capital | VC firm | Morton Grove, IL | Pre-seed, Seed | Healthtech, AI, SaaS | New deal, Oct 2026 | $40M (SEC Form D, 2024) | 2026-11-05 | https://theinvestordatabase.com/investors/alliance-venture-capital/ |
| Bison Ventures | VC firm | San Francisco, CA | Pre-seed, Seed, Series A, Series B | Healthtech, AI, Energy, Biotech | New fund, Oct 2026 | $160M (SEC Form D, 2025) | 2026-11-04 | https://theinvestordatabase.com/investors/bison-ventures/ |
| First In Ventures | VC firm | Hobe Sound, FL | Pre-seed, Seed | Healthtech, Biotech, AI, Climate Tech | New fund, Sep 2026 | $22M (SEC Form D, 2026) | 2026-11-04 | https://theinvestordatabase.com/investors/first-in-ventures/ |
| Leo Capital | VC firm | San Francisco, CA | Pre-seed, Seed | Healthtech, AI, Fintech, Insurtech | New deal, Oct 2026 | $20M (SEC Form D, 2026) | 2026-11-04 | https://theinvestordatabase.com/investors/leo-capital/ |
| Cybernetix Ventures | VC firm | Boston, MA | Pre-seed, Seed, Series A | Healthtech, Robotics, Industrial Tech, Logistics | New fund, Aug 2026 | $100M (SEC Form D, 2025) | 2026-11-04 | https://theinvestordatabase.com/investors/cybernetix-ventures/ |
| January Ventures | VC firm | Wellesley Hills, MA | Pre-seed | Healthtech, AI, Future of Work, Space | New fund, Jun 2026 | $15M (SEC Form D, 2021) | 2026-11-04 | https://theinvestordatabase.com/investors/january-ventures/ |
| Heinz Ventures, LLC | VC firm | Memphis, TN | Pre-seed, Seed | Healthtech, Medtech | New deal, Aug 2026 | $10M (SEC Form D, 2024) | 2026-11-04 | https://theinvestordatabase.com/investors/heinz-ventures-llc/ |
| TreeoVC | VC firm | Pompano Beach, FL | Pre-seed, Seed | Healthtech, AI, Robotics, Deep Tech | New fund, Aug 2026 | $9M (SEC Form D, 2023) | 2026-11-04 | https://theinvestordatabase.com/investors/treeovc/ |
| Rebellion Ventures | VC firm | San Francisco, CA | Pre-seed, Seed | Healthtech, AI, Logistics, Industrial Tech | New fund, Oct 2026 | $13M (SEC Form D, 2022) | 2026-11-04 | https://theinvestordatabase.com/investors/rebellion-ventures/ |
| Great Oaks Venture Capital | VC firm | New York, NY | Pre-seed, Seed, Series A | Healthtech, Generalist, SaaS, Fintech | Portfolio news, Sep 2026 | $20M (SEC Form ADV) | 2026-11-05 | https://theinvestordatabase.com/investors/great-oaks-venture-capital/ |
| Quiet Capital | VC firm | San Francisco, CA | Pre-seed | Healthtech, AI, SaaS, Fintech | New fund, Nov 2026 | $500M (SEC Form D, 2021) | 2026-11-04 | https://theinvestordatabase.com/investors/quiet-capital/ |
| How Women Invest | VC firm | Oakland, CA | Pre-seed, Seed, Series A, Series B | Healthtech, AI, B2B, Climate Tech | New fund, Sep 2026 | $12M (SEC Form D, 2026) | 2026-11-04 | https://theinvestordatabase.com/investors/how-women-invest/ |
| Equal Opportunity Ventures | VC firm | Cambridge, MA | Pre-seed | Healthtech, Fintech, Food and Beverage, Ecommerce | New deal, Apr 2026 | $152M (SEC Form ADV) | 2026-11-05 | https://theinvestordatabase.com/investors/equal-opportunity-ventures/ |
| Founder Collective | VC firm | Cambridge, MA | Pre-seed, Seed | Healthtech, AI, Ecommerce, Generalist | New deal, Jul 2026 | $95M (SEC Form D, 2023) | 2026-11-05 | https://theinvestordatabase.com/investors/founder-collective/ |
| First Round | VC firm | Philadelphia, PA | Pre-seed, Seed, Series A | Healthtech, AI, Developer Tools, Fintech | New fund, Aug 2026 | $500M (SEC Form D, 2022) | 2026-11-04 | https://theinvestordatabase.com/investors/first-round/ |
| Newtopia Investments | VC firm | United States | Pre-seed, Seed | Healthtech, AI, Fintech, Ecommerce | New fund, Jul 2026 | $75M (SEC Form D, 2026) | 2026-11-04 | https://theinvestordatabase.com/investors/newtopia-investments/ |

You are seeing 25 of 225. The full list adds 200 more investors and 1,162 named decision-makers.

Get all 225 investors and 1,162 named contacts, $49, one-time: https://theinvestordatabase.com/buy/list/pre-seed-healthtech-investors-us
This page: https://theinvestordatabase.com/lists/pre-seed-healthtech-investors-us/

## Method and limits
- Source: All 225 rows carry an SEC filing (Form D or Form ADV). All 225 have a website we checked. Filing date and fund size are SEC data where a filing exists. Stage, sector and check size are our research.
- Inclusion rule: Organizations that back startups. Individuals, buyout funds and firms we found to be inactive are left out. Sector: the firm states healthtech and digital health as a focus on its own site, or we observed it in the firm's portfolio. Stage: the firm states that it invests at pre-seed.
- Order: Activity score out of 100: recency of the latest fund filing or dated deal (30: full marks within 3 months, then stepping down at 6, 12 and 24 months), share of the observed portfolio in this sector (20; half of that when the sector is stated only), stage focus (15: all of it when pre-seed is the only stage the firm states, split evenly when it states more), stated focus on the US (15: full marks when the firm names the US as where it invests, half when it says global), size of the fund on file on a log scale (12) and completeness of the public record (8). Stage and regional focus are our research, not an SEC figure. It is a measure of activity and fit, not of quality or returns.
- Fill rates: Of 225 rows: stage 225, sector 225, fund size 201, website 225. In the paid file: named decision-makers on 223 rows, firm email on 77, LinkedIn page on 127, check size on 32.

## Questions
### How many pre-seed healthtech investors in the US are there?
We list 225 as of November 2026. 140 of the 225 have a fund filing or a dated deal in the last 12 months. The cities with the most are New York (30), San Francisco (19) and Palo Alto (17).

### Which pre-seed healthtech investors in the US raised a new fund in the last 12 months?
114 of the 225 have a fund filing dated in the last 12 months. The most recent on this list are Quiet Capital (Nov 2026), Branch Venture Partners (Nov 2026) and LightX Capital (Nov 2026).

### What is the typical fund size of pre-seed healthtech investors in the US?
The median fund size on file for this list is $50M, across the 178 firms with a size on an SEC Form D. The fund on file is each firm's main fund, which is not always its newest. The other 47 do not disclose a size there.

### How do I contact pre-seed healthtech investors in the US?
The paid file holds 1,162 named decision-makers across 223 of these 225 and a firm email for 77. We publish the address a firm lists itself, never a personal email. Each free row links to a profile with the firm's website.

### Where does the data on pre-seed healthtech investors in the US come from?
All 225 rows have an SEC filing on file (Form D or Form ADV). Filing date and fund size come from the filing. Stage, sector and check size are our research. Rows on this list were last checked on 6 Nov 2026 at the latest. The whole file is re-verified twice a year.