76 Series A medtech investors in the US
We list 76 Series A medtech investors in the US as of November 2026: each has an SEC filing on file, and the list was last checked on 6 Nov 2026. The cities with the most head offices on this list are New York (8), Menlo Park (7) and Boston (6).
Top 5 Series A medtech investors in the US, ranked by recent fund activity
Among firms with a published profile and a dated fund or deal in the last 24 months. The rule: Activity score out of 100: recency of the latest fund filing or dated deal (30: full marks within 3 months, then stepping down at 6, 12 and 24 months), share of the observed portfolio in this sector (20; half of that when the sector is stated only), stage focus (15: all of it when Series A is the only stage the firm states, split evenly when it states more), stated focus on the US (15: full marks when the firm names the US as where it invests, half when it says global), size of the fund on file on a log scale (12) and completeness of the public record (8). Stage and regional focus are our research, not an SEC figure. It is a measure of activity and fit, not of quality or returns. The same rule orders the whole list; it is repeated in the method box.
Khosla Ventures
Type: VC firm · HQ: Menlo Park, CA · Stages: Pre-seed, Seed, Series A, Growth · Focus: Medtech, AI, Consumer, B2B · Latest activity: New fund, Aug 2026 · Fund size on file: $1.9B (SEC Form D, 2025)
Latest fund filing dated Aug 2026; $1.9B fund on file (SEC Form D, 2025); states medtech and medical devices as a focus; backs pre-seed, seed, Series A; names the US as where it invests; 8 named decision-makers on file.
Cybernetix Ventures
Type: VC firm · HQ: Boston, MA · Stages: Pre-seed, Seed, Series A · Focus: Medtech, Robotics, Industrial Tech, Logistics · Latest activity: New fund, Aug 2026 · Fund size on file: $100M (SEC Form D, 2025)
Latest fund filing dated Aug 2026; $100M fund on file (SEC Form D, 2025); states medtech and medical devices as a focus; backs pre-seed, seed, Series A; names the US as where it invests; 2 named decision-makers on file.
SHD Partners
Type: VC firm · HQ: Dallas, TX · Stages: Seed, Series A · Focus: Medtech, Healthtech, Biotech · Latest activity: Portfolio news, Nov 2026 · Private fund assets: $61M (SEC Form ADV)
Portfolio news dated Nov 2026; $61M on file (SEC Form ADV); 53% of its observed portfolio is medtech and medical devices; backs seed, Series A; 6 named decision-makers on file.
HC9 Ventures
Type: VC firm · HQ: Havertown, PA · Stages: Seed, Series A · Focus: Medtech, Healthtech, AI, Fintech · Latest activity: New fund, Oct 2026 · Fund size on file: $85M (SEC Form D, 2025)
Latest fund filing dated Oct 2026; $85M fund on file (SEC Form D, 2025); 81% of its observed portfolio is medtech and medical devices; backs seed, Series A; 3 named decision-makers on file.
Great Oaks Venture Capital
Type: VC firm · HQ: New York, NY · Stages: Pre-seed, Seed, Series A · Focus: Medtech, Healthtech, Generalist, SaaS · Latest activity: Portfolio news, Sep 2026 · Private fund assets: $20M (SEC Form ADV)
Portfolio news dated Sep 2026; $20M on file (SEC Form ADV); 22% of its observed portfolio is medtech and medical devices; backs pre-seed, seed, Series A; names the US as where it invests; 6 named decision-makers on file.
First 25 of 76 Series A medtech investors in the US
| Investor | Type | HQ | Stagesour research | Focusour research | Latest fund or deal | Fund sizeas filed or stated | Checked | Contacts |
|---|---|---|---|---|---|---|---|---|
| Khosla Ventures | VC firm | Menlo Park, CA | Pre-seed, Seed, Series A, Growth | Medtech, AI, Consumer, B2B | New fund, Aug 2026 | $1.9B (SEC Form D, 2025) | 4 Nov 2026 | 8 names · Unlock |
| Cybernetix Ventures | VC firm | Boston, MA | Pre-seed, Seed, Series A | Medtech, Robotics, Industrial Tech, Logistics | New fund, Aug 2026 | $100M (SEC Form D, 2025) | 4 Nov 2026 | 2 names · Unlock |
| SHD Partners | VC firm | Dallas, TX | Seed, Series A | Medtech, Healthtech, Biotech | Portfolio news, Nov 2026 | $61M (SEC Form ADV) | 5 Nov 2026 | 6 names, firm email · Unlock |
| HC9 Ventures | VC firm | Havertown, PA | Seed, Series A | Medtech, Healthtech, AI, Fintech | New fund, Oct 2026 | $85M (SEC Form D, 2025) | 4 Nov 2026 | 3 names · Unlock |
| Great Oaks Venture Capital | VC firm | New York, NY | Pre-seed, Seed, Series A | Medtech, Healthtech, Generalist, SaaS | Portfolio news, Sep 2026 | $20M (SEC Form ADV) | 5 Nov 2026 | 6 names · Unlock |
| Arboretum Ventures | VC firm | Ann Arbor, MI | Series A, Series B | Medtech, Healthtech, Biotech | Portfolio news, Mar 2026 | $250M (SEC Form D, 2022) | 5 Nov 2026 | 7 names · Unlock |
| 25Madison Ventures | VC firm | New York, NY | Pre-seed, Seed, Series A | Medtech, Healthtech, AI, Logistics | New fund, Oct 2026 | $50M (SEC Form D, 2026) | 4 Nov 2026 | 8 names, firm email · Unlock |
| Winter Street Ventures | VC firm | Boston, MA | Seed, Series A | Medtech, Healthtech, AI | New fund, Jun 2026 | $75M (SEC Form D, 2026) | 4 Nov 2026 | 2 names, firm email · Unlock |
| Felicis | VC firm | Menlo Park, CA | Seed, Series A | Medtech, AI, Developer Tools, Healthtech | New deal, Oct 2026 | $900M (SEC Form D, 2025) | 5 Nov 2026 | 8 names · Unlock |
| How Women Invest | VC firm | Oakland, CA | Pre-seed, Seed, Series A, Series B | Medtech, Healthtech, AI, B2B | New fund, Sep 2026 | $12M (SEC Form D, 2026) | 4 Nov 2026 | 8 names · Unlock |
| Distributed Ventures | VC firm | Chicago, IL | Seed, Series A | Medtech, Fintech, Insurtech, Healthtech | New deal, Jul 2026 | $90M (SEC Form D, 2021) | 5 Nov 2026 | 5 names, firm email · Unlock |
| NCN Management Company PF | VC firm | Nashville, TN | Seed, Series A | Medtech, Healthtech, SaaS | Portfolio news, Apr 2026 | $35M (SEC Form ADV) | 5 Nov 2026 | 5 names, firm email · Unlock |
| Claritas Signal Partners | VC firm | Nashville, TN | Seed, Series A, Series B, Growth | Medtech, Healthtech, AI, Media | New deal, Aug 2026 | $14M (SEC Form D, 2021) | 5 Nov 2026 | 8 names · Unlock |
| Ansa | VC firm | New York, NY | Series A, Series B, Growth | Medtech, AI, Cybersecurity, Healthtech | New fund, May 2026 | $200M (SEC Form D, 2026) | 4 Nov 2026 | 4 names, firm email · Unlock |
| First Round | VC firm | Philadelphia, PA | Pre-seed, Seed, Series A | Medtech, AI, Developer Tools, Fintech | New fund, Aug 2026 | $500M (SEC Form D, 2022) | 4 Nov 2026 | 8 names · Unlock |
| S3 Ventures | VC firm | Austin, TX | Seed, Series A, Series B | Medtech, Healthtech, Developer Tools, SaaS | New fund, Sep 2025 | $150M (SEC Form D, 2022) | 4 Nov 2026 | 1 name · Unlock |
| Wavemaker Three-Sixty Health | VC firm | Pasadena, CA | Pre-seed, Seed, Series A | Medtech, Healthtech, AI | New fund, Dec 2024 | $100M (SEC Form D, 2021) | 5 Nov 2026 | 8 names · Unlock |
| Star51 Capital | VC firm | New York, NY | Seed, Series A, Series B, Growth | Medtech, Healthtech, AI, Robotics | New deal, Sep 2026 | 4 Nov 2026 | 3 names, firm email · Unlock | |
| FCA Venture Management Group | VC firm | Nashville, TN | Seed, Series A, Series B | Medtech, Healthtech, AI, Biotech | Portfolio news, May 2026 | $58M (SEC Form ADV) | 5 Nov 2026 | 8 names · Unlock |
| Sandbox Clinical Ventures | VC firm | Chicago, IL | Seed, Series A, Series B, Growth | Medtech, Insurtech, Healthtech, AI | New fund, Sep 2026 | $100M (SEC Form D, 2021) | 4 Nov 2026 | 8 names, firm email · Unlock |
| Roo Capital | VC firm | Coconut Grove, FL | Pre-seed, Seed, Series A, Growth | Medtech, AI, Healthtech, Future of Work | New fund, Aug 2026 | $125M (SEC Form D, 2026) | 4 Nov 2026 | 8 names, firm email · Unlock |
| Cultivation Capital | VC firm | St. Louis, MO | Seed, Series A, Series B | Medtech, Healthtech, Biotech, SaaS | New fund, Sep 2026 | $100M (SEC Form D, 2022) | 4 Nov 2026 | 8 names · Unlock |
| Healthier Capital | VC firm | Menlo Park, CA | Series A | Medtech, Healthtech, AI, SaaS | New fund, Nov 2025 | $200M (SEC Form D, 2024) | 4 Nov 2026 | 8 names · Unlock |
| Cornucopian Capital | VC firm | Montclair, NJ | Pre-seed, Seed, Series A, Series B | Medtech, Healthtech, AI, Biotech | New fund, Aug 2026 | $12M (SEC Form D, 2024) | 4 Nov 2026 | 1 name · Unlock |
| Define Ventures | VC firm | San Francisco, CA | Pre-seed, Seed, Series A, Series B | Medtech, Healthtech, AI, Future of Work | New deal, Apr 2026 | $425M (SEC Form D, 2022) | 5 Nov 2026 | 8 names · Unlock |
You are seeing 25 of 76. The full list adds 51 more investors and 401 named decision-makers.
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How these 76 break down
By US state
| US state | On this list | Share |
|---|---|---|
| California | 24 | 32% |
| New York | 8 | 11% |
| Massachusetts | 7 | 9% |
| Tennessee | 5 | 7% |
| Texas | 4 | 5% |
| Pennsylvania | 4 | 5% |
| Illinois | 4 | 5% |
| New Jersey | 3 | 4% |
| Michigan | 2 | 3% |
| Florida | 2 | 3% |
By type
| Type | On this list | Share |
|---|---|---|
| VC firm | 75 | 99% |
| Corporate VC | 1 | 1% |
Method and limits
- Source
- All 76 rows carry an SEC filing (Form D or Form ADV). All 76 have a website we checked. Filing date and fund size are SEC data where a filing exists. Stage, sector and check size are our research.
- Inclusion rule
- Organizations that back startups. Individuals, buyout funds and firms we found to be inactive are left out. Sector: the firm states medtech and medical devices as a focus on its own site, or we observed it in the firm's portfolio. Stage: the firm states that it invests at Series A.
- Order
- Firms with a published profile come first. Activity score out of 100: recency of the latest fund filing or dated deal (30: full marks within 3 months, then stepping down at 6, 12 and 24 months), share of the observed portfolio in this sector (20; half of that when the sector is stated only), stage focus (15: all of it when Series A is the only stage the firm states, split evenly when it states more), stated focus on the US (15: full marks when the firm names the US as where it invests, half when it says global), size of the fund on file on a log scale (12) and completeness of the public record (8). Stage and regional focus are our research, not an SEC figure. It is a measure of activity and fit, not of quality or returns.
- Last refreshed
- November 2026. Rows on this list were checked between 4 Nov 2026 and 6 Nov 2026.
- Fill rates
- Of 76 rows: stage 76, sector 76, fund size 65, website 76. In the paid file: named decision-makers on 73 rows, firm email on 31, LinkedIn page on 50, check size on 10.
- Corrections
- Email hello@theinvestordatabase.com or use the update form. We act within 5 working days.
Questions
How many Series A medtech investors in the US are there?
We list 76 as of November 2026. 36 of the 76 have a fund filing or a dated deal in the last 12 months. The cities with the most are New York (8), Menlo Park (7) and Boston (6).
Which Series A medtech investors in the US raised a new fund in the last 12 months?
23 of the 76 have a fund filing dated in the last 12 months. The most recent on this list are 25Madison Ventures (Oct 2026), Switchboard (Oct 2026) and HC9 Ventures (Oct 2026).
What is the typical fund size of Series A medtech investors in the US?
The median fund size on file for this list is $90M, across the 49 firms with a size on an SEC Form D. The fund on file is each firm's main fund, which is not always its newest. The other 27 do not disclose a size there.
How do I contact Series A medtech investors in the US?
The paid file holds 401 named decision-makers across 73 of these 76 and a firm email for 31. We publish the address a firm lists itself, never a personal email. Each free row links to a profile with the firm's website.
Where does the data on Series A medtech investors in the US come from?
All 76 rows have an SEC filing on file (Form D or Form ADV). Filing date and fund size come from the filing. Stage, sector and check size are our research. Rows on this list were last checked on 6 Nov 2026 at the latest. The whole file is re-verified twice a year.
Broader lists
Medtech venture capital firms in the US (350)Series A investors in the US (372)Series A medtech investors (125)
Related lists
Series A AI investors in the US (280)Series A SaaS investors in the US (256)Seed medtech investors in the US (205)Series A healthtech investors in the US (164)Series A fintech investors in the US (145)Pre-seed medtech investors in the US (95)Series A consumer investors in the US (80)Series A B2B investors in the US (79)Series A deep tech investors in the US (73)Growth-stage medtech investors in the US (69)Series A cybersecurity investors in the US (64)Series A hardware investors in the US (61)Series A industrial tech investors in the US (61)Series A climate tech investors in the US (60)Series A energy investors in the US (60)Series A biotech investors in the US (59)Series A developer tools investors in the US (50)Series A robotics investors in the US (44)
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