--- title: "18 Venture Capital Firms in Missouri (Nov 2026): by City" last_updated: "2026-11-05" rows: "18" free_rows: "10" source: "SEC filings" canonical: "https://theinvestordatabase.com/lists/venture-capital-firms-in-missouri/" --- # 18 venture capital firms in Missouri We list 18 venture capital firms in Missouri as of November 2026: each has an SEC filing on file, and the list was last checked on 5 Nov 2026. The cities with the most head offices on this list are St. Louis (10), Kansas City (5) and Clayton (1). - 18 firms - 6 with a fund filing or dated deal in the last 12 months - $42M median fund size on file (SEC Form D, 11 firms) - 59 named decision-makers on file ## First 10 of 18 venture capital firms in Missouri | Investor | Type | HQ | Stages (our research) | Focus (our research) | Latest fund or deal | Fund size | Checked | Profile | |---|---|---|---|---|---|---|---|---| | SixThirty Ventures, LLC | VC firm | Clayton, MO | Seed, Series A | Fintech, AI, Healthtech, Insurtech | New deal, Sep 2026 | $134M (SEC Form ADV) | 2026-11-05 | https://theinvestordatabase.com/investors/sixthirty-ventures-llc/ | | Flyover Capital | VC firm | Kansas City, MO | Seed, Series A | AI, Fintech, Healthtech, SaaS | New fund, Oct 2026 | $75M (SEC Form D, 2026) | 2026-11-04 | https://theinvestordatabase.com/investors/flyover-capital/ | | Cultivation Capital | VC firm | St. Louis, MO | Seed, Series A, Series B | Healthtech, Biotech, SaaS, Agritech | New fund, Sep 2026 | $100M (SEC Form D, 2022) | 2026-11-04 | https://theinvestordatabase.com/investors/cultivation-capital/ | | Redbud VC | VC firm | Columbia, MO | Pre-seed | Healthtech, Agritech, AI, Climate Tech | New fund, Sep 2026 | $25M (SEC Form D, 2025) | 2026-11-04 | https://theinvestordatabase.com/investors/redbud-vc/ | | iSelect Fund | VC firm | St. Louis, MO | | Healthtech, Agritech, Food and Beverage, Biotech | New fund, Dec 2024 | $97M (SEC Form D, 2024) | 2026-11-05 | https://theinvestordatabase.com/investors/iselect-fund/ | | Ascension Ventures | Corporate VC | St. Louis, MO | Growth | Healthtech, Medtech, Biotech | | $475M (SEC Form ADV) | 2026-11-05 | https://theinvestordatabase.com/investors/ascension-ventures/ | | Stakehouse | VC firm | St. Louis, MO | Pre-seed | Edtech | New fund, Aug 2025 | $30M (SEC Form D, 2025) | 2026-11-04 | https://theinvestordatabase.com/investors/stakehouse/ | | KCRise Fund | VC firm | Kansas City, MO | Seed | AI, Healthtech, Future of Work, Edtech | New deal, Dec 2023 | $42M (SEC Form D, 2020) | 2026-11-05 | https://theinvestordatabase.com/investors/kcrise-fund/ | | Abstraction Capital | VC firm | Kansas City, MO | Pre-seed, Seed | AI, Developer Tools, SaaS, Data | New fund, Jun 2024 | $20M (SEC Form D, 2020) | 2026-11-05 | https://theinvestordatabase.com/investors/abstraction-capital/ | | GX Expedition | VC firm | St. Louis, MO | | | New fund, May 2026 | $50M (SEC Form D, 2026) | 2026-11-04 | https://theinvestordatabase.com/investors/gx-expedition/ | You are seeing 10 of 18. The full list adds 8 more firms and 59 named decision-makers. Get all 18 firms and 59 named contacts, $49, one-time: https://theinvestordatabase.com/buy/list/venture-capital-firms-in-missouri This page: https://theinvestordatabase.com/lists/venture-capital-firms-in-missouri/ ## Method and limits - Source: All 18 rows carry an SEC filing (Form D or Form ADV). 9 of the 18 have a website we checked; the other 9 rest on the filing or register entry alone. Filing date and fund size are SEC data where a filing exists. Stage, sector and check size are our research. - Inclusion rule: Organizations that back startups. Individuals, buyout funds and firms we found to be inactive are left out. This list holds VC firms, fund managers and corporate venture arms; accelerators and angel networks are in their own lists. Place: head office in Missouri. - Order: Activity score out of 100: recency of the latest fund filing or dated deal (50: full marks within 3 months, then stepping down at 6, 12 and 24 months), size of the fund on file on a log scale (35) and completeness of the public record (15). It is a measure of activity and fit, not of quality or returns. - Fill rates: Of 18 rows: stage 8, sector 9, fund size 17, website 9. In the paid file: named decision-makers on 12 rows, firm email on 4, LinkedIn page on 8, check size on 0. ## Questions ### How many VC firms are in Missouri? We list 18 as of November 2026. 6 of the 18 have a fund filing or a dated deal in the last 12 months. By type: VC firm (17) and Corporate VC (1). ### Which cities in Missouri have the most VC firms? St. Louis (10), Kansas City (5) and Clayton (1). ### Which Missouri VC funds filed with the SEC in the last 12 months? 5 of the 18 have a fund filing dated in the last 12 months. The most recent on this list are Flyover Capital (Oct 2026), Cultivation Capital (Sep 2026) and Redbud VC (Sep 2026). ### What stages do venture capital firms in Missouri back? Of the 8 with a stage on file, seed (5), pre-seed (3) and Series A (3). A firm can back more than one stage, and 10 rows have no stage on file yet. ### Where does the data on venture capital firms in Missouri come from and how often is it updated? All 18 rows have an SEC filing on file (Form D or Form ADV). Filing date and fund size come from the filing. Stage, sector and check size are our research. Rows on this list were last checked on 5 Nov 2026 at the latest. The whole file is re-verified twice a year. ### Can I download the list of venture capital firms in Missouri as a spreadsheet? Yes. The file holds all 18 rows in Excel and CSV, with 59 named decision-makers and 4 firm emails, for $49 one-time. 10 rows are free on this page.