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Updated November 2026

25 venture capital firms in San Diego

We list 25 venture capital firms in San Diego as of November 2026: each has an SEC filing on file, and the list was last checked on 6 Nov 2026. The cities with the most head offices on this list are San Diego (11), La Jolla (6) and Encinitas (3).

25firms
13with a fund filing or dated deal in the last 12 months
$18Mmedian fund size on file (SEC Form D, 15 firms)
80named decision-makers on file

Top 10 venture capital firms in San Diego, ranked by recent fund activity

Among firms with a published profile and a dated fund or deal in the last 24 months. The rule: Activity score out of 100: recency of the latest fund filing or dated deal (50: full marks within 3 months, then stepping down at 6, 12 and 24 months), size of the fund on file on a log scale (35) and completeness of the public record (15). It is a measure of activity and fit, not of quality or returns. The same rule orders the whole list; it is repeated in the method box.

  1. IceNine Capital

    Type: VC firm · HQ: San Diego, CA · Stages: Seed · Focus: Space, Defense Tech, Industrial Tech, Deep Tech · Latest activity: New fund, Oct 2026

    Latest fund filing dated Oct 2026; backs seed; 5 named decision-makers on file.

  2. Vesta Ventures

    Type: VC firm · HQ: Encinitas, CA · Focus: Proptech, AI, Fintech, SaaS · Latest activity: New fund, Jul 2026 · Fund size on file: $10M (SEC Form D, 2026)

    Latest fund filing dated Jul 2026; $10M fund on file (SEC Form D, 2026); 5 named decision-makers on file.

  3. Harpoon Ventures

    Type: VC firm · HQ: San Diego, CA · Focus: AI, Mobility, Space, Defense Tech · Latest activity: New fund, Feb 2026 · Fund size on file: $140M (SEC Form D, 2026)

    Latest fund filing dated Feb 2026; $140M fund on file (SEC Form D, 2026); 3 named decision-makers on file.

  4. TVC Capital

    Type: VC firm · HQ: La Jolla, CA · Stages: Growth · Focus: Healthtech, SaaS, B2B, AI · Latest activity: Portfolio news, Jan 2025 · Private fund assets: $308M (SEC Form ADV)

    Portfolio news dated Jan 2025; $308M on file (SEC Form ADV); backs growth-stage; 4 named decision-makers on file.

  5. Avalon BioVentures

    Type: VC firm · HQ: La Jolla, CA · Stages: Pre-seed · Focus: Biotech, Healthtech, Space · Latest activity: Portfolio news, Nov 2024 · Fund size on file: $200M (SEC Form D, 2021)

    Portfolio news dated Nov 2024; $200M fund on file (SEC Form D, 2021); backs pre-seed; 8 named decision-makers on file.

  6. Behind Genius Ventures

    Type: VC firm · HQ: San Diego, CA · Stages: Pre-seed, Seed · Focus: AI, Media, Developer Tools, Future of Work · Latest activity: New fund, Jul 2026 · Fund size on file: $2M (SEC Form D, 2026)

    Latest fund filing dated Jul 2026; $2M fund on file (SEC Form D, 2026); backs pre-seed, seed; 5 named decision-makers on file.

  7. Channel Equity Partners

    Type: VC firm · HQ: San Diego, CA · Stages: Growth · Focus: SaaS, B2B, AI · Latest activity: New fund, Apr 2026 · Fund size on file: $20M (SEC Form D, 2024)

    Latest fund filing dated Apr 2026; $20M fund on file (SEC Form D, 2024); backs growth-stage; 2 named decision-makers on file.

  8. Kaleida Capital

    Type: VC firm · HQ: San Diego, CA · Focus: Healthtech, AI, Biotech, Deep Tech · Latest activity: New fund, Jun 2026

    Latest fund filing dated Jun 2026; 4 named decision-makers on file.

  9. Radicle Growth

    Type: VC firm · HQ: San Diego, CA · Focus: Agritech, AI, Healthtech, Climate Tech · Latest activity: New deal, Jun 2026

    Dated new deal in Jun 2026; 2 named decision-makers on file.

  10. Newtown Partners

    Type: VC firm · HQ: San Diego, CA · Stages: Seed, Series A · Focus: Logistics, Fintech · Latest activity: Portfolio news, Oct 2025 · Private fund assets: $28M (SEC Form ADV)

    Portfolio news dated Oct 2025; $28M on file (SEC Form ADV); backs seed, Series A; 1 named decision-maker on file.

First 12 of 25 venture capital firms in San Diego

InvestorTypeHQStagesour researchFocusour researchLatest fund or dealFund sizeas filed or statedCheckedContacts
IceNine CapitalVC firmSan Diego, CASeedSpace, Defense Tech, Industrial Tech, Deep TechNew fund, Oct 20264 Nov 20265 names, firm email · Unlock
Vesta VenturesVC firmEncinitas, CAProptech, AI, Fintech, SaaSNew fund, Jul 2026$10M (SEC Form D, 2026)4 Nov 20265 names, firm email · Unlock
Harpoon VenturesVC firmSan Diego, CAAI, Mobility, Space, Defense TechNew fund, Feb 2026$140M (SEC Form D, 2026)4 Nov 20263 names · Unlock
TVC CapitalVC firmLa Jolla, CAGrowthHealthtech, SaaS, B2B, AIPortfolio news, Jan 2025$308M (SEC Form ADV)5 Nov 20264 names, firm email · Unlock
Avalon BioVenturesVC firmLa Jolla, CAPre-seedBiotech, Healthtech, SpacePortfolio news, Nov 2024$200M (SEC Form D, 2021)5 Nov 20268 names, firm email · Unlock
Behind Genius VenturesVC firmSan Diego, CAPre-seed, SeedAI, Media, Developer Tools, Future of WorkNew fund, Jul 2026$2M (SEC Form D, 2026)4 Nov 20265 names · Unlock
Channel Equity PartnersVC firmSan Diego, CAGrowthSaaS, B2B, AINew fund, Apr 2026$20M (SEC Form D, 2024)4 Nov 20262 names · Unlock
Kaleida CapitalVC firmSan Diego, CAHealthtech, AI, Biotech, Deep TechNew fund, Jun 20264 Nov 20264 names, firm email · Unlock
Radicle GrowthVC firmSan Diego, CAAgritech, AI, Healthtech, Climate TechNew deal, Jun 20265 Nov 20262 names, firm email · Unlock
Newtown PartnersVC firmSan Diego, CASeed, Series ALogistics, FintechPortfolio news, Oct 2025$28M (SEC Form ADV)5 Nov 20261 name, firm email · Unlock
Avalon VenturesVC firmLa Jolla, CAPre-seed, SeedBiotech$236M (SEC Form ADV)5 Nov 20266 names, firm email · Unlock
Clear Creek Investments, LLCVC firmSolana Beach, CAAny stageClimate Tech, Energy, Food and Beverage$86M (SEC Form ADV)5 Nov 20262 names, firm email · Unlock

You are seeing 12 of 25. The full list adds 13 more firms and 80 named decision-makers.

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How these 25 break down

By city

CityOn this listShare
San Diego1144%
La Jolla624%
Encinitas312%
Solana Beach28%

By stage

StageOn this listShare
Pre-Seed520%
Seed624%
Growth28%

Stage is our research. A firm can back more than one stage.

By sector

SectorOn this listShare
AI1040%
SaaS832%
Healthtech728%
Fintech520%
Biotech520%
Hardware416%
Space312%
Deep Tech312%
Medtech312%
Climate Tech312%
Defense Tech28%
Industrial Tech28%

Sector is our research. A firm can carry more than one sector.

Method and limits

Source
All 25 rows carry an SEC filing (Form D or Form ADV). 15 of the 25 have a website we checked; the other 10 rest on the filing or register entry alone. Filing date and fund size are SEC data where a filing exists. Stage, sector and check size are our research.
Inclusion rule
Organizations that back startups. Individuals, buyout funds and firms we found to be inactive are left out. This list holds VC firms, fund managers and corporate venture arms; accelerators and angel networks are in their own lists. Place: head office in San Diego, matched on city and state.
Order
Firms with a published profile come first. Activity score out of 100: recency of the latest fund filing or dated deal (50: full marks within 3 months, then stepping down at 6, 12 and 24 months), size of the fund on file on a log scale (35) and completeness of the public record (15). It is a measure of activity and fit, not of quality or returns.
Last refreshed
November 2026. Rows on this list were checked between 4 Nov 2026 and 6 Nov 2026.
Fill rates
Of 25 rows: stage 11, sector 16, fund size 20, website 15. In the paid file: named decision-makers on 23 rows, firm email on 10, LinkedIn page on 9, check size on 0.
Corrections
Email hello@theinvestordatabase.com or use the update form. We act within 5 working days.

How we verify

Questions

How many VC firms are in San Diego?

We list 25 as of November 2026. 13 of the 25 have a fund filing or a dated deal in the last 12 months.

Which cities in San Diego have the most VC firms?

San Diego (11), La Jolla (6) and Encinitas (3).

Which San Diego VC funds filed with the SEC in the last 12 months?

11 of the 25 have a fund filing dated in the last 12 months. The most recent on this list are Trybe Sports (Oct 2026), IceNine Capital (Oct 2026) and GV (Sep 2026).

What stages do venture capital firms in San Diego back?

Of the 11 with a stage on file, seed (6), pre-seed (5) and growth-stage (2). A firm can back more than one stage, and 14 rows have no stage on file yet.

Where does the data on venture capital firms in San Diego come from and how often is it updated?

All 25 rows have an SEC filing on file (Form D or Form ADV). Filing date and fund size come from the filing. Stage, sector and check size are our research. Rows on this list were last checked on 6 Nov 2026 at the latest. The whole file is re-verified twice a year.

Can I download the list of venture capital firms in San Diego as a spreadsheet?

Yes. The file holds all 25 rows in Excel and CSV, with 80 named decision-makers and 10 firm emails, for $49 one-time. 12 rows are free on this page.

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